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. 2022 Nov 4;12(11):1786. doi: 10.3390/life12111786

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(a) Coronal section of Slc:SD rat after 160 min administration. (b) BPA biodistribution image generated by MALDI-MSI (drawn with [BPA + H]⁺ (m/z 210.084)). A large amount of BPA is present in the lateral ventricle (➣). The distribution in the image shows a different distribution from the tumor-derived peak (c) and the endogenous biomolecule-derived peak (d) following CSF administration. (c) The mass image obtained from peaks at m/z 210.026 originated in tumor. (d) The mass image obtained from peaks at m/z 307.042 originated from endogenous biomolecule.