Table 1.
Numbers of Capsules Each Day | Before | 1st Month | 2nd Month | 3rd Month |
None | 40 | 40 | 43 | 38 (95%) |
1 capsule | 40 | 40 | 36 | 18 * (45%) # |
2 capsules | 40 | 39 | 34 | 15 * (37.5) # |
3 capsules | 40 | 38 | 32 | 12 * (30%) # |
Group 1 (N = 40 eyes): no proteases were taken (placebo group) (vitamin C 10 mg daily); Group 2 (N = 40 eyes): all patients took 1 capsule with mixed proteases, including 190 mg bromelain, 95 mg papain, and 95 mg ficin every day; Group 3 (N = 40 eyes): all patients took 2 capsules daily; Group 4 (N = 40 eyes): all patients took 3 capsules daily. p < 0.05 was denoted as symbol * by the Scheffe test; p < 0.05 was denoted as symbol # by the Williams’ test.