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. 2022 Nov 2;14(11):2434. doi: 10.3390/v14112434

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Schematic illustration of PEDV infection in host cells and the role of pro/antiviral host factors in PEDV replication. There are four main stages in the PEDV life cycle: attachment, entry, replication, and release. Interaction of host proteins with PEDV proteins is indicated by dotted lines; proviral host factors are indicated in blue text; antiviral host factors are indicated in red text; downstream activation is indicated by black arrows; inhibition or degradation of target genes is indicated by red lines ending in dashes.