Skip to main content
. 2022 Oct 24;14(11):2279. doi: 10.3390/pharmaceutics14112279

Figure 5.

Figure 5

Specific means of siRNA and nucleus damage in favor of MTPTT. (A) Schematic illustration of the synthesis of PDA-coated nucleic acid nanogel and the mechanism of siRNA-mediated MTPTT induced by PEG-PDA-Nanogel [34]. Copyright © 2022, Elsevier. (B) Schematic illustration of the design of GNRs-siRNA in the improved MTPTT platform [82]. Copyright © 2022, Elsevier. (C) Schematic diagram of the cancer cell membrane and nucleus organelle dual-target V2C-TAT@Ex-RGD nanoagents for multimodal imaging-guided MTPTT in the NIR-II biowindow [83]. Copyright © 2022, American Chemical Society. (D) Illustration of DNAzyme-based nanosponges for highly efficient PTT [84]. Copyright © 2022, The Author(s).