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. 2022 Oct 31;14(11):2347. doi: 10.3390/pharmaceutics14112347

Table 3.

Summarized results of statistical analysis of experimental data with ANOVA showing values of fitted models for dependent variables along with predicted and obtained outcomes of optimized LSP-NLCs.

Response F-Value Model
p-Value
Lack of Fit Lack of Fit
p-Value
R2 Adjusted R2 Predicted Mean Value Obtained Value Error (%)
Particle size (nm) 103.83 <0.0001 3.03 0.0756 0.9454 0.9363 157.9 152.0 ± 4.7 3.7
PDI 139.21 <0.0001 1.50 0.3039 0.9775 0.9705 0.240 0.230 ± 0.05 4.2
Entrapment efficiency (%) 240.21 <0.0001 3.58 0.0533 0.9869 0.9827 85.0 88.0 ± 2.4 3.5

The obtained values are presented as mean ± S.D. (n = 3). Error (%) = (obtained value–predicted value)/predicted value × 100.