Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Nov 10;10(11):1894. doi: 10.3390/vaccines10111894

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

CpG 1018 increases pdm09 vaccine-induced HI titer. Old mice (78 weeks) were intradermally immunized with 0.5 µg pdm09 vaccine alone () or in the presence of CpG 1018 adjuvant (40 µg, ) or left non-immunized (). Young adult mice (6–8 weeks) were intradermally immunized with the same amount of pdm09 vaccine () or left non-immunized (). Serum HI titer was measured 3 weeks after immunization. n = 4–7. One-way ANOVA with Fisher’s LSD test was used to compare differences between groups. *, p < 0.05; **, p < 0.01; ***, p < 0.001.

Inline graphic — CpG 1018 increases pdm09 vaccine-induced HI titer. Old mice (78 weeks) were intradermally immunized with 0.5 µg pdm09 vaccine alone () or in the presence of CpG 1018 adjuvant (40 µg, ) or left non-immunized (). Young adult mice (6–8 weeks) were intradermally immunized with the same amount of pdm09 vaccine () or left non-immunized (). Serum HI titer was measured 3 weeks after immunization. n = 4–7. One-way ANOVA with Fisher’s LSD test was used to compare differences between groups. *, p < 0.05; **, p < 0.01; ***, p < 0.001.