Table 1.
Overview of the most common commercial NGS platforms and instruments.
| Brand | Instrument | Key Applications | Run Time (h) | Max. Output (Gb) |
Max. Read Length (Bases) |
|---|---|---|---|---|---|
| Illumina, Inc. | NextSeq 550 | Targeted Gene Sequencing Transcriptome Sequencing |
12–30 | 120 | PE150 |
| NextSeq 1000 and 2000 | WGS (limited samples) WES Targeted Gene Sequencing Transcriptome Sequencing |
11–48 | 360 | PE150 | |
| NovaSeq 6000 | WGS WES Targeted Gene Sequencing Transcriptome Sequencing Methylation Sequencing |
13–44 * | 6000 | PE250 | |
| NovaSeq X Series | WGS (large sample number) WES Targeted Gene Sequencing Transcriptome Sequencing Methylation Sequencing |
13–48 * | 16,000 | PE150 | |
| MGI Tech | DNBSEQ-G50 | Targeted Gene Sequencing | 9–40 | 150 | PE150 |
| DNBSEQ-G400 | WGS (limited samples) WES Transcriptome Sequencing |
13–109 * | 1440 | PE300 | |
| DNBSEQ-T7 | WGS (large sample number) WES Targeted Gene Sequencing Transcriptome Sequencing |
24–30 | 6000 | PE150 | |
| Ion Torrent | Ion GeneStudio S5/Plus/Prime | WES (limited samples) Targeted Gene Sequencing |
6–19 | 15/30/50 | SE200/SE400/SE200 |
| Genexus System | WES (limited samples) Targeted Gene Sequencing |
2–3 | 15 | SE200 |
* Depends on the flow cell used. WES, whole-exome sequencing; WGS, whole-genome sequencing; Gb, gigabases; PE, paired-end; SE, single-end.