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Growth of M. tuberculosis H37Rv in lungs, livers, spleens, and kidneys of Nramp1−/− and wild-type (Nramp1+/+) mice inoculated i.v. with 104 CFU of bacilli. There was no significant difference in the ability of mutant and wild-type mice to control bacterial replication over 130 days of infection except for day 130 in the spleen, where the differences between the means was significant (P < 0.05). Means ± standard errors of five mice per group per time point are shown.
