ABCG |
ATP binding cassette subfamily G |
ACC |
Acetyl-CoA carboxylase |
AMPK |
AMP-activated protein kinase |
APAP |
Acetaminophen (Paracetamol) |
BA |
Bile acid |
BSEP |
Bile salt efflux pump |
CD36 |
Cluster of differentiation 36; fatty acid translocase |
CoA |
Coenzyme A |
CPT1 |
Carnitine palmitoyltransferase-1 |
CYP |
Cytochrome P450 superfamily |
DILI |
Drug-induced liver injury |
EET |
Epoxyeicosatrienoic acid |
EPHX2 |
Epoxide hydrolase 2 |
FA |
Fatty acid |
FABP |
Fatty acid binding proteins |
FAS |
Fatty acid synthetase |
FGF |
Fibroblast growth factor |
FXR |
Farnesoid X receptor |
HNF4α |
Hepatocyte nuclear factor 4 alpha |
LDLr |
Low-density lipoprotein receptor |
LRH-1 |
Liver receptor homolog-1 |
LTB |
Leukotriene |
MDR3 |
Multidrug resistance protein 3 |
MRP |
Multidrug resistance associated protein |
NAFLD |
Nonalcoholic fatty liver disease |
NASH |
Nonalcoholic steatohepatits |
NF-κB |
Nuclear factor kappa B |
NTCP |
Sodium-taurocholate cotransporting polypeptide |
OAT |
Organic anion transporter |
OATP |
Organic anion transporting polypeptides |
OCA |
Obeticholic acid |
OCT |
Organic cation transporter |
OSTα/β |
Organic solute transporter alpha/beta |
PPAR |
Peroxisome proliferator-activated receptor |
RXR |
Retinoid X receptor |
SHP-1 |
Small heterodimer protein 1 |
SIRT1 |
Sirtuin 1; class III NAD+ dependent histone deacetylase |
SREBP-1c |
Sterol regulatory element-binding protein 1c |
UGT |
UDP-glucuronosyltransferase enzymes |
VLDL |
Very-low density lipoprotein |