Figure 1.

G-1 significantly decreases tumor growth in nude mice. (A) U87MG cells were subcutaneously injected into nude mice. Tumor volume change (TVC: for each mouse, the difference between tumor volume at each point of the experiment and tumor volume at the time of animal randomization) was measured during 2 weeks of treatment every 2 days. (B) Quantification of Ki-67-positive cells in tumors of the vehicle or G-1-treated mice. The data are presented as the mean ± SD. Significance level was determined using t-tests, with * indicating p < 0.05. Vehicle, n = 3; and G-1, n = 4.