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. 2022 Nov 18;23(22):14309. doi: 10.3390/ijms232214309

Figure 6.

Figure 6

GSEA signature enrichment of G-1 is mainly related to the cell cycle and Myc pathways. GSEA analysis using the gene expression profile of U251 cells exposed to 1 µM of G-1 for 72 h showed significant positive enrichment for gene sets that are linked to mitotic spindle and chromatid separation and gene sets related to Myc pathway signatures.