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. 2022 Nov 20;23(22):14427. doi: 10.3390/ijms232214427

Figure 3.

Figure 3

(A) The application of chitosan loaded baicalein nanoparticles (L-B-NPs) for asthma treatment. Reproduced with permission from [31], © 2022 The Author(s). Published by Elsevier B.V. on behalf of King Saud University. (B) The chitosan-based swellable microparticles for loading budesonide reduced the levels of IL-4 and IL-5 in-vivo and improved pathophysiology. Reproduced with permission from Statistics: aa p <0.01; *** p <0.001 vs. control group; ### p < 0.001, ## p < 0.01, # p < 0.05 vs. model group [34], © 2022 Elsevier B.V. (C) HA decorated, FA loaded CS nanoparticles (FACHA NPs) were administered by nebulization and exerted a therapeutic effect on OVA-sensitized and challenged asthmatic mice. (D) FACHA NPs did not cause significant damage to the lungs, liver, kidneys, pancreas or spleen in vivo. Reproduced with permission from [36], © 2022 Elsevier B.V.