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. 2022 Nov 1;14(11):2361. doi: 10.3390/pharmaceutics14112361

Figure 7.

Figure 7

NMR structure of the complex between the unimolecular parallel G-quadruplex o-tel17 of sequence d[TTGGT(GGGT)3] and (A) d(AG) or (C) cGAMP. 5′- and 3′-ends of the G-quadruplex are at the top and bottom, respectively. Details of the ligand binding are highlighted in (B) for d(AG) and (D) for cGAMP. Adapted with permission from ref. [71], Copyright 2019 American Chemical Society.