Table 2.
The associations between ICD-related gene signature risk and patients’ clinical features in the training set.
| Variables | Low-Risk Group (n = 208) |
High-Risk Group (n = 207) |
|||
|---|---|---|---|---|---|
| NO. | % | NO. | % | p | |
| Age | 0.797 | ||||
| ≤60 | 88 | 42.3 | 85 | 41.1 | |
| >60 | 120 | 57.7 | 122 | 58.9 | |
| Gender | 0.212 | ||||
| Male | 113 | 54.3 | 125 | 60.4 | |
| Female | 95 | 45.7 | 82 | 39.6 | |
| ECOG | 0.141 | ||||
| 1–2 | 179 | 86.1 | 167 | 80.7 | |
| 3–4 | 29 | 13.9 | 40 | 19.3 | |
| Ann Anbor stage | |||||
| I–II | 108 | 51.9 | 92 | 44.4 | 0.127 |
| III–IV | 100 | 48.1 | 115 | 55.6 | |
| Extranodal sites | 0.031 | ||||
| <2 | 171 | 82.2 | 152 | 73.4 | |
| ≥2 | 37 | 17.8 | 55 | 26.6 | |
| LDH | 0.131 | ||||
| Normal | 80 | 38.5 | 65 | 31.4 | |
| Elevated | 128 | 61.5 | 142 | 68.6 | |
| COO | 0.000 | ||||
| GCB | 123 | 59.1 | 83 | 40.1 | |
| Non-GCB | 85 | 40.9 | 124 | 59.9 | |
Abbreviations: ECOG, Eastern Cooperative Oncology Group; LDH, lactate dehydrogenase; COO, cell of origin; GCB, germinal center B cells.