Table 1.
Current Treatments for wet AMD.
Treatments | Formulation | Procedure | Administration | Frequency | Main Function |
---|---|---|---|---|---|
Anti-VEGF therapy | Antiangiogenic drugs | Intravitreal injection, infusion | Monthly/weekly | More than 1 | Blocking or neutralizing VEGF expression |
Laser photocoagulation | Laser light with special contact lens | Laser surgery | Monthly | More than 1 | Utilizing heat from a laser to shrink or destroy abnormal blood vessels |
Photodynamic combined therapy | Laser- and light-activated drugs | Intravenous injection and shining a laser into the eye | Monthly | More than 1 | Creating blood clots to seal the abnormal blood vessels |
Cell therapy | Pluripotent stem cell-derived RPE cells | Subretinal injection or transplantation | Once | 1 | Reversal of the degenerative loss of RPE cells |