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. 2022 Nov 21;17:5511–5524. doi: 10.2147/IJN.S381815

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© 2022 Jiang et al.

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Physiochemical characterization of KGN-MNPs. (A) Illustration of the procedures used to synthesize KGN-MNPs. (B) Size distributions of agglomerations and TEM images of KGN-MNPs and MNPs. (C) FTIR spectra of KGN-MNPs and MNPs. (D) The hysteresis loops of KGN-MNPs and MNPs at 25 °C. (E) pI value measurements of KGN-MNPs and MNPs. (F) Thermogravimetric analysis. (G) XRD patterns of KGN-MNPs and MNPs. (H) Ex vitro release of KGN from the KGN-MNPs in PBS solution at 37 °C.

Abbreviations: KGN, kartogenin; MNPs, magnetic nanoparticles; KGN-MNPs, KGN loaded MNPs.