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. 2022 Nov 13;23(22):13990. doi: 10.3390/ijms232213990

Figure 5.

Figure 5

Modulation and targeting by iron chelators of iron metabolic pathways and activities of biomolecules, organelles and cells related to cancer formation, proliferation, metastasis and drug resistance affecting almost all types of cancer. NDRG1: N-MYC downstream-regulated gene-1; OXPHOS: oxidative phosphorylation; ROS: reactive oxygen species; STEAP4: six-transmembrane epithelial antigen of prostate, family member 4.