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Phenotype of cells responding in vitro. Proliferation (A), IFN-γ (B), and IL-10 (C) responses of lymph node cells from mice rendered tolerant (open symbols) and mice not rendered tolerant (closed symbols) cultured in the presence of anti-CD4 (squares) or anti-CD8 (triangles) are shown. No cytokines were detectable in supernatants of cultures from mice rendered tolerant. Results of one experiment, representative of two for each mouse group, are shown.
