Table 1.

The time-dependent physical stabilities of mRNA encapsulating LNPs.

Time (Days)	Size (nm)	PDI	Zeta-Potential (mV)	mRNA Retention Rate (%)
0	112.2 ± 1.3	0.081 ± 0.022	−5.72 ± 1.41	93.96 ± 1.19
1	114.9 ± 2.9	0.086 ± 0.039	−6.29 ± 2.34	95.67 ± 5.06
3	113.1 ± 2.2	0.061 ± 0.018	−6.13 ± 1.26	93.00 ± 2.50
5	111.6 ± 2.0	0.047 ± 0.043	−4.88 ± 0.67	95.45 ± 0.96
7	112.5 ± 1.0	0.065 ± 0.027	−4.15 ± 1.62	95.58 ± 1.46

Data are represented as the mean ± S.D., n = 3. Statistical analyses were performed using Tukey’s test.