Table 5.

Effects of the light exposure on particle properties of the mRNA encapsulating LNPs.

Condition	Size (nm)	PDI	Zeta-Potential (mV)	mRNA Retention Rate (%)
No exposure	116.8 ± 5.8	0.045 ± 0.016	−4.37 ± 0.32	93.06 ± 2.32
Light exposure (2 × 104 lx·h)	116.1 ± 6.8	0.079 ± 0.060	−4.71 ± 2.29	94.77 ± 1.54
Light exposure (1.2 × 106 lx·h)	114.3 ± 5.1	0.050 ± 0.009	−5.24 ± 1.06	95.11 ± 1.30

Data are represented as the mean ± S.D., n = 3. Statistical analysis was performed using Dunnett’s test versus the no-exposure group.