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. 2022 Nov 9;27(22):7719. doi: 10.3390/molecules27227719

Table 3.

In silico toxicity.

Comp. FRC-FM TD50-M
Unit: mg/kg/day
DT-P A-M MTD-F * O-R- LD50 * C-LOAEL-R * Skin Irritancy Ocular Irritancy
Compound 10 Non-Carcinogen 55.367 Non-Toxic Non-Mutagen 0.095 1.810 0.100 Non-Irritant Mild
Sorafenib Carcinogen 19.236 Toxic Non-Mutagen 0.089 0.823 0.005

* Unit: g/kg body weight.