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. 2022 Oct 22;15(11):1306. doi: 10.3390/ph15111306

Table 2.

Release Kinetics of optimum ALN formulation.

Models		Formulation Code
Models		Free Amygdalin Solution	Optimum ALN	Free Amygdalin Gel	Optimum ALN Gel
Zero-order	R²	0.8306	0.8931	0.8301	0.9813
	AIC	74.16	68.9844	70.5037	43.3294
	MSC	1.1574	1.7850	1.1545	3.5498
First-order	R²	0.9810	0.9778	0.9719	0.9666
	AIC	52.6823	53.2812	52.5032	49.1558
	MSC	3.3502	3.3553	2.9546	2.9672
Higuchi	R²	0.9944	0.9099	0.9939	0.8702
	AIC	40.2658	67.2772	36.825	62.7321
	MSC	4.5919	1.9557	4.5224	1.6095
Korsmeyer–Peppas	R²	0.999	0.9521	0.9985	0.9830
	AIC	24.6978	62.9484	24.4751	44.3785
	MSC	6.1487	2.3886	5.7574	3.4449
Weibull	R²	0.9843	0.997	0.9920	0.9873
	AIC	54.7420	36.8968	43.4813	43.5044
	MSC	3.1442	4.9938	3.8568	3.5323
Hixson–Crowell	R²	0.9709	0.9720	0.9477	0.9750
	AIC	57.0082	55.5794	58.7300	46.2607
	MSC	2.9176	3.1255	2.3319	3.2567