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. 2022 Oct 28;15(11):1335. doi: 10.3390/ph15111335

Table 2.

4-Amino and 4-ureido pyridazinones synthesized and screened against FABP4.

graphic file with name pharmaceuticals-15-01335-i002.jpg
Comp. R2 R4 R6
25a CH3 NHCONH2 Ph
25b cC6H11 NHCONH2 Ph
25c C2H5 NHCONH2 Ph
25d iC3H7 NHCONH2 Ph
25e nC3H7 NHCONH2 Ph
25f nC4H9 NHCONH2 Ph
28 H NHCONH2 Ph
29a CH3 NHCOCH3 Ph
29b CH3 NHCOC2H5 Ph
29c CH3 NHCOiC3H7 Ph
29d CH3 NHCOnC3H7 Ph
30a CH3 NH-(3-CN)-Ph Ph
30b CH3 NH-(2-CN)-Ph Ph
31a CH3 NH-(3-CONH2)-Ph Ph
31b CH3 NH-(2-CONH2)-Ph Ph
35 CH3 graphic file with name pharmaceuticals-15-01335-i003.jpg Ph
39a CH3 NHCONH2 cC6H11
39b CH3 NHCONH2 iC3H7
40 H NHCONH2 2-(OH)-Ph
43 CH3 NHCONH2 2-(OH)-Ph
49 CH3 NHCONH2 2-pyridinyl
51 CH3 CONH2 Ph
55 Ph NHCONH2 CH3