FIG. 3.

UTI by E. coli Dr⁺ in C3H/HeJ mice leads to inflammatory response in fetus and poor development of fetal organs. (A) Representative fetal pathology in sections obtained from mice infected at 35% gestation with E. coli Dr⁺ and sacrificed after preterm delivery showed 3+ chronic infiltration of PMNs and poor development of the fetal organs. Abbreviations: B, immature bone. Magnification, ×50. (B) Normal histopathological appearance of fetal section of the E. coli Dr⁻ or control group showing normal organ development with no infiltrating PMNs. Abbreviations: B, bone; S, skeletal muscle; L, lung. Magnification, ×50.