TABLE 2.

Quantitative bacterial tissue cultures and determination of fetal birth weight outcome in infected and control groups of C3H/HeJ mice

Group	Mean no. (CFU/g) of bacteria ± SEM found by bacterial culture						Mean fetal wtb (g) ± SEM (no. of fetuses)
	After deliverya			At day 17 of gestationb
	Kidney	Fetus	Spleen	Kidney	Fetus	Spleen
E. coli Dr+	5 × 108 ± 1 × 108c	3 × 108 ± 2 × 108d	ND	8 × 109 ± 2 × 109e	4 × 109 ± 2 × 109f	>108e (4/8)g	0.644 ± 0.030h (6)
E. coli Dr−	5 × 107 ± 2 × 107	7 × 106 ± 7 × 106	ND	5 × 109 ± 2 × 109	1 × 107 ± 1 × 107	>108 (2/8)	0.813 ± 0.021 (6)
Control	0	0	ND	0	0	0	0.88 ± 0.10 (5)

^aDay 7 E. coli-infected and control groups of mice were sacrificed after the delivery, and tissues were collected for E. coli bacterial cultures. These data were obtained from 10 mice in the E. coli Dr⁺ group and 12 mice in the E. coli Dr⁻ group and 6 mice in the control group. ND, not determined. 

^bDay 7 E. coli-infected and control groups of mice were sacrificed on day 17 of gestation, tissues were collected for bacterial cultures, and fetuses were removed and carefully weighed for each group of mice. This experiment included eight mice in each E. coli Dr⁺ or E. coli Dr⁻ group and five mice in the control group. 

^cSignificantly different from the value obtained for the E. coli Dr⁻ group (P = 0.004). 

^dSignificantly different from the value obtained for the E. coli Dr⁻ group (P = 0.02). 

^eNot significantly different from the value obtained for the E. coli Dr⁻ group (P > 0.05). 

^fSignificantly different from the value obtained for the E. coli Dr⁻ group (P = 0.05). 

^gThe number of mice with >10⁸ CFU per g of spleen to the total number of mice in the group is shown in the parentheses (P > 0.05). 

^hSignificantly different from the values obtained for the E. coli Dr⁻ and control groups (P = 0.003).