Table 1.
Clinical and ECG features of the 35 ALVC female patients.
| Overall n = 35 |
Childbearing Women n = 16 |
Nulliparous Women n = 19 |
p | |
|---|---|---|---|---|
| Probands | 18 (51%) | 8 (50%) | 10 (53%) | 0.573 |
| Age at evaluation | 40 ± 11 | 45 ± 9 | 36 ± 11 | 0.050 |
| Family history of SCD | 18 (51%) | 7 (44%) | 11 (58%) | 0.505 |
| Family history of DCM | 9 (26%) | 5 (31%) | 4 (21%) | 0.700 |
| Family history of ALVC | 18 (51%) | 8 (50%) | 10 (52%) | 1.000 |
| Family history of ARVC | 11 (31%) | 5 (31%) | 6 (32%) | 1.000 |
| Family history of HF | 11 (31%) | 8 (50%) | 3 (16%) | 0.065 |
| Myocarditis-like episodes | 4 (11%) | 1 (6%) | 3 (16%) | 0.608 |
| Ventricular arrhythmias | 32 (91%) | 15 (94%) | 17 (89%) | 1.000 |
| Frequent PVBs | 13 (37%) | 4 (25%) | 9 (42%) | 0.311 |
| NSVT | 12(41%) | 7 (50%) | 5 (32%) | 0.468 |
| Sustained VT | 7 (20%) | 3 (19%) | 4 (21%) | 0.799 |
| ICD | 10 (29%) | 5 (31%) | 5 (32%) | 0.747 |
| Normal ECG | 10 (28%) | 4 (25%) | 6 (31%) | 0.099 |
| Low QRS voltages (limb leads) | 23 (65%) | 13 (81%) | 10 (53%) | 0.152 |
| Low QRS voltages (precordial leads) | 11 (31%) | 5 (31%) | 6 (32%) | 1.000 |
| Negative T wave V1-V3 | 4 (11%) | 1 (6%) | 3 (16%) | 0.608 |
| Negative T wave V4-V6 | 7 (20%) | 3 (19%) | 4 (21%) | 1.000 |
| Negative T wave inferior leads | 6 (17%) | 2 (12%) | 4 (21%) | 0.666 |
SCD: sudden cardiac death; DCM: dilated cardiomyopathy; ALVC: arrhythmogenic left ventricular cardiomyopathy; ACM: arrhythmogenic right ventricular cardiomyopathy; HF: heart failure; PVBs: premature ventricular beats; VT: ventricular tachycardia; NSVT: non-sustained VT; and ICD: implantable cardioverter–defibrillator.