TABLE 1.
Demographic Characteristics of the Study Participants and the CERAD-NB Results
| CO | iNPH | AD | P CO-iNPH | P CO-AD | P iNPH-AD | |
|---|---|---|---|---|---|---|
| N | 37 | 10 | 21 | |||
| Demographics | ||||||
| Age in years | 71.0 (5.1) | 75.9 (5.7) | 71.1 (6.9) | 0.061 | 1.000 | 0.098 |
| Women | 20 (54.1) | 7 (70.0) | 13 (61.9) | 0.481 | 0.594 | 0.712 |
| Education in years | 12.6 (4.3) | 10.0 (3.5) | 12.5 (4.2) | 0.261 | 1.000 | 0.354 |
| ApoE ε4 carrier | 14 (37.8) | 0 (0.0) | 15 (78.9) | 0.022 | 0.005 | <0.001 |
| CERAD-NB (maximum score) | ||||||
| Verbal fluency (animals) | 25.1 (7.3) | 15.5 (5.2) | 15.9 (6.3) | <0.001 | <0.001 | 1.000 |
| Boston Naming Test (15) | 13.4 (1.7) | 12.7 (1.9) | 11.1 (3.3) | 1.000 | 0.002 | 1.000 |
| MMSE (30) | 28.4 (1.5) | 24.7 (3.6) | 23.9 (3.0) | <0.001 | <0.001 | 1.000 |
| Wordlist learning (30) | 23.1 (3.1) | 15.9 (2.0) | 13.3 (2.2) | <0.001 | <0.001 | 0.043 |
| Wordlist savings (%) | 95.1 (10.6) | 56.3 (24.5) | 38.6 (29.9) | <0.001 | <0.001 | 0.099 |
| Wordlist recognition (%) | 98.2 (3.6) | 83.5 (21.5) | 74.8 (11.6) | <0.001 | <0.001 | 0.106 |
| Constructional praxis (11) | 10.5 (1.0) | 9.2 (1.8) | 9.4 (2.7) | 0.133 | 0.092 | 1.000 |
| Constr. praxis savings (%) | 95.1 (10.1) | 87.8 (26.1) | 60.8 (39.3) | 1.000 | <0.001 | 0.020 |
| Clock drawing (6) | 5.5 (0.6) | 4.4 (1.2) | 4.2 (1.6) | 0.013 | <0.001 | 1.000 |
| Global Memory Score (30) | 27.8 (1.8) | 21.8 (2.7) | 16.9 (3.3) | <0.001 | <0.001 | <0.001 |
Values are presented as mean and SD, except for sex and ApoE ε4 carrier status, which are shown as number and percentage of the participants.
Bold P values indicate significant differences between groups (P ≤ 0.05).
AD indicates Alzheimer’s disease; CERAD-NB, the Consortium to Establish a Registry for Alzheimer’s disease neuropsychological test battery; CO, control; iNPH, idiopathic normal pressure hydrocephalus; MMSE, Mini-Mental State Examination; N, number of participants.