Table 1.
Fractional enrichments (%) of 13C-isotopomers that generate or are associated with lipogenic [U-13C]acetyl-CoA (13CIUA) for selected hepatic metabolite pools for a group of four mice provided with 2H2O and [U-13C]glucose tracers, and a group of five mice provided with 2H2O and [U-13C]fructose. Values are reported as means ± SE. N.D. not determined.
| 13CIUA (Equation) | |||||
|---|---|---|---|---|---|
| Experiment | Hepatic Glucose-6-P (Equation (1)) |
Dietary Glucose (Equation (2)) |
GNG precursors (Equation (3a,b)) |
Triose-P (Equation (4)) |
Acetyl-CoA (Equation (5)) |
| [U-13C]Glucose and unlabeled fructose (n = 4) |
3.78 ± 0.74 | 5.47 ± 1.25 | 1.30 ± 0.15 | 2.50 ± 0.66 | 1.53 ± 0.43 |
| Unlabeled glucose and [U-13C]fructose (n = 5) |
5.06 ± 0.34 | N.D. | 14.99 ± 1.24 | 8.99 ± 1.05 | 4.32 ± 0.50 |