Table 2.
HARD (%) | No Treatment (%) | Difference in Responder Rate* | p † | |
---|---|---|---|---|
No. | 107 | 33 | ||
At least one-point improvement from baseline | 87 (81.3) | 2 (6.1) | 75.2 | <0.001 |
95% CI, % | 72.62–88.19‡ | 0.74–20.23‡ | 62.27–88.22§ |
HARD, hyaluronic acid filler Restylane Defyne.
*Difference = HARD responder rate − no-treatment responder rate.
†Fisher exact test for responder rate. Missing data were imputed using the baseline observation carried forward method.
‡Calculated using the Clopper-Pearson method.
§Calculated using the Wald approximation with a continuity correction.