TABLE 3.
Effects of a Pharmacy-based CIVAS on IAPEs
IAPE Prevalence | Mixed-Effects Logistic Regression Analysis*† | |||
---|---|---|---|---|
All Admixtures, n/N (%) | After Exclusion of Matched Admixtures*, n/N (%) | Univariable Analysis (n = 995), Odds Ratio (95% Confidence Interval) | Multivariable Analysis‡ (n = 994), Adjusted Odds Ratio (95% Confidence Interval) | |
Measurement period | ||||
Clinical wards: usual care | 148/282 (52.5) | 134/264 (50.8) | Reference | Reference |
Hospital pharmacy: CIVAS period 1 | 63/796 (7.9) | 28/319 (8.8) | 0.06 (0.02–0.16) | 0.06 (0.02–0.18) |
Hospital pharmacy: CIVAS period 2 | 14/543 (2.6) | 11/419 (2.6) | 0.02 (0.005–0.05) | 0.02 (0.004–0.05) |
*Only the first admixture was included for matched admixtures, that is, admixtures with the following identical characteristics: staff member, patient, medication name, time window, and date of admixture preparation.
†Mixed-effects logistic regression analysis was used to account for within-subject correlations because of repeated measurements by staff members and patients.
‡Odds ratios have been adjusted for time window and day of admixture preparation.
Odds ratios in bold have a P < 0.05.