Table 3.
Overall Population |
New-Onset HF |
Worsening CHF |
p Value | |
---|---|---|---|---|
n = 772 | n = 339 | n = 433 | ||
eGFR (mL/min) (n = 761) |
46 [28–67] | 56 [39–77] | 40 [25–58] | <0.001 |
Creatinine (mmol/L) (n = 751) |
133 [95–190] | 110 [84–149] | 145 [112–210] | <0.001 |
Hemoglobin (g/dL) (n = 754) |
12.6 [11–14] | 13 [11.2–14.6] | 12 [10.6–14] | <0.001 |
Arterial blood lactate (mmol/L) (n = 684) | 3 [2–4.75] | 3 [2–5] | 2.9 [2–4] | 0.121 |
Arterial blood lactate > 2.2 (mmol/L) (n = 684) |
422 (61.7) | 200 (65.8) | 222 (58.4) | 0.049 |
pH (n = 668) |
7.39 [7.28–7.46] | 7.37 [7.26–7.44] | 7.40 [7.30–7.46] | 0.007 |
PT (%) (n = 731) |
59 [37–77] | 70 [52–85] | 48 [29–68] | <0.001 |
SGOT (IU/L) (n = 547) |
90 [39–301] | 125 [51–377] | 69 [35–220] | 0.521 |
SGPT (IU/L) (n = 559) |
59 [27–183] | 71 [33–194] | 48 [24–177] | 0.815 |
Bilirubin (mmol/L) (n = 544) |
16 [9–29] | 13 [8–23] | 20 [11–34] | <0.001 |
BNP (ng/L) (n = 264) |
1150 [476–2778] | 835 [277–2051] | 1511 [687–3157] | 0.182 |
NT-pro-BNP (ng/L) (n = 224) |
9277 [4045–23,810] |
6306 [2063–11,730] |
12,652 [5360–30,000] |
0.006 |
BNP or NT-pro-BNP by deciles (n = 480) | ||||
1 | 47 (9.8) | 36 (18.8) | 11 (3.8) | |
2 | 49 (10.2) | 27 (14) | 22 (7.6) | |
3 | 51 (10.6) | 24 (12.5) | 27 (9.4) | |
4 | 45 (9.3) | 18 (9.4) | 27 (9.4) | |
5 | 47 (9.8) | 21 (10.9) | 26 (9) | <0.001 |
6 | 52 (10.8) | 14 (7.2) | 38 (13.2) | |
7 | 46 (9.5) | 13 (6.8) | 33 (11.5) | |
8 | 50 (10.4) | 14 (7.2) | 36 (12.5) | |
9 | 41 (8.5) | 9 (4.7) | 32 (11.1) | |
10 | 52 (10.8) | 16 (8.3) | 36 (12.5) | |
CRP (mg/L) (n = 406) |
28 [9–69] | 34 [8–98] | 26 [10–58] | 0.006 |
In this table, continuous variables are expressed as median [IQR]. HF = heart failure, CHF = chronic heart failure, eGFR = estimated glomerular filtration rate, IQR = interquartile range, PT = prothrombin time, SGOT = Serum Glutamooxaloacetate Transferase, SGPT = Serum Glutamopyruvate Transferase, CRP = C-reactive protein, BNP = Brain natriuretic peptide.