Table 1.
Baseline patients’ characteristics.
| Variable | Total (n = 163) | PT-GBD (n = 33) | EUS-GBD (n = 21) |
LC (n = 81) |
OC (n = 25) |
p Value |
|---|---|---|---|---|---|---|
| Age Median (IQR) |
77 (71–82) | 83 (75–87) | 84 (81–89) | 74 (70–79) | 74 (69–80) | <0.001 |
| Male No (%) |
90 (56%) | 12 (36%) | 10 (48%) | 51 (63%) | 17 (68%) | 0.03 |
| BMI Median (IQR) |
26.2 (24.2–29.1) | 26.7 (23.6–29.6) | 25.8 (21.6–28) | 25.8 (24.3–25.8) | 27.3 (25.2–31.2) | 0.24 |
| Clinical Fraility Scale Score (median [range]) | 3.00 [1.00, 8.00] | 6.00 [2.00, 8.00] | 4.00 [2.00, 8.00] | 3.00 [1.00, 8.00] | 3.00 [2.00, 7.00] | <0.001 |
| ACS score Median (IQR) |
6.45 (3.88–17.02) |
17.6 (16.4,23) | 6.1 (5.3–7.3) | 4 (2.8–6) | 17.5 (12.9–20.6) | <0.001 |
| Non operative management (NOM) failure | 36 (22.5) | 17 (51.5) | 4 (19.0) | 11 (13.6) | 4 (16.0) | <0.001 |
| Previous AC No (%) |
41 (26%) | 12 (38%) | 8 (38%) | 17 (21%) | 4 (16%) | 0.10 |
| Previous ERCP No (%) |
17 (11%) | 3 (9%) | 6 (29%) | 7 (9%) | 1 (4%) | 0.12 |
| Anticoagulant therapy No (%) |
47 (29%) | 10 (30%) | 12 (57%) | 18 (22%) | 7 (28%) | 0.02 |
| WBC No (×1000) |
12 (8.5–16.5) | 6.9 (0.7–16.1) | 14.7 (7.5–17.1) | 12.6 (10.4–17) | 11.7 (10.7–14.4) | 0.02 |
| Hb [g/dl] Median (IQR) |
12.9 (10.3–13.4) | NR | NR | 13.1 (10.3–14.2) | 12.4 (11–14.3) | 0.11 |
| CRP [mg/dl] Median (IQR) |
11.5 (4–22.7) | 15 (11.2–24) | 6.15 (1.87–25) | 8.32 (2.4–19.1) | 13.5 (7.16–24.8) | 0.04 |
| Total Bilirubin [mg/dl] Median (IQR) |
1.2 (0.73–2) | 1.2 (0.7–2.4) | 1.1 (0.62–1.53) | 1.32 (0.88–2.08) | 0.9 (0.68–1.87) | 0.43 |
| INR Median (IQR) |
1.21 (1.1–1.37) | 1.32 (1.21–1.69) | 1.23 (1.1–1.36) | 1.15 (1.07–1.31) | 1.2 (1.13–1.29) | 0.008 |
Continuous variables were reported as median values and interquartile range. Comparisons were performed with ANOVA for continuous variables and chi square test for categorical ones. Significances were reported in bold. Previous AC: previous episode of acute cholecystitis; ERCP: Endoscopic retrograde cholangiopancreatography; WBC: white blood cells; Hb: Hemoglobin; CPR: c-reactive protein; INR: International Normalized Ratio. Bold values are statistically significant.