Table 1.
MIC values for the TMA analogues in EMSA experiments.
| Derivative | IUPAC Name (ID Name) | MIC 1 |
|---|---|---|
| GY955 | 6-phenyl-4,4′-dimethyl-angelicin (6-PhDMA) | 30 μM |
| GY956 | 4-isopropyl-6-phenyl-4′-methyl-angelicin (IPPhMA) | 60 μM |
| GY957 | 4-cyclopropyl-6 phenyl-4′-methyl-angelicin (CPPhMA) | >100 μM |
| GY963 | 4-cyclopropyl-6,4′-dimethyl-angelicin (CPDMA) | 100 μM |
| GY964 | 4-phenyl-6,4′-dimethyl-angelicin (4-PhDMA) | 30 μM |
| GY965 | 4-isopropyl-6-methyl-angelicin (IPMA) | 80 μM |
| GY966 | 4-cyclopropyl-6-methyl-angelicin (CPMA) | 18 μM |
| GY967 | 4-isopropyl-6-ethyil-angelicin (IPEA) | >100 μM |
| GY971 | 6-p-aminophenyl-4,4′-dimethyl-angelicin (pANDMA) | <12.5 μM |
1 Minimal Inhibitory Concentration. In the EMSA experiments, 12.5 μM was the lowest concentration used.