Table 3.
Pro-apoptotic activity (%) of TMA and GY964 (4-PhDMA), dissolved in DMSO (Vehicle), and GY971a (pANDMA), dissolved in water, on CFBE41o- cells.
| Sample | Live | Early Apoptosis | Late Apoptosis | Dead | Total Apoptosis |
|---|---|---|---|---|---|
| Untreated cells (C-) | 93.25 | 0.65 | 4.00 | 2.10 | 4.65 |
| Vehicle | 95.64 | 0.53 | 2.86 | 0.98 | 3.38 |
| TMA 50 nM | 92.69 | 0.59 | 5.07 | 1.65 | 5.67 |
| TMA 100 nM | 93.40 | 0.70 | 5.00 | 0.90 | 5.70 |
| TMA 200 nM | 93.50 | 1.16 | 3.75 | 1.60 | 4.91 |
| GY964 50 nM | 94.80 | 0.50 | 3.25 | 1.45 | 3.75 |
| GY964 100 nM | 91.82 | 3.45 | 4.09 | 0.63 | 7.54 |
| GY964 200 nM | 93.85 | 0.80 | 3.65 | 1.70 | 4.45 |
| GY971a 50 nM | 94.20 | 0.95 | 3.20 | 1.65 | 4.15 |
| GY971a 100 nM | 94.75 | 0.70 | 3.25 | 1.30 | 3.95 |
| GY971a 200 nM | 92.95 | 0.45 | 5.00 | 1.60 | 5.45 |