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. 2022 Nov 7;14(21):8818–8838. doi: 10.18632/aging.204371

Table 2. Summary of the meta-analysis of m6A regulators and prognosis in cancer patients.

Regulators Outcome Studies HR 95% Cl P-value Heterogeneity Effects model
I2 P-value
METTL3 OS 21 1.75 1.32–2.31 0 78.10% 0 Random
DFS 7 2.02 1.54–2.64 0 52% 0.052 Random
METTL14 OS 4 0.55 0.43–0.69 0 0.00% 0.392 Random
KIAA1429 OS 2 2.35 1.40–3.93 0.001 37.20% 0.207 Random
METTL16 OS 2 1.75 0.84–3.65 0.137 82.20% 0.018 Random
ALKBH5 OS 8 1.09 0.75–1.57 0.657 62.50% 0.009 Random
FTO OS 10 1.01 0.72–1.41 0.966 74.70% 0 Random
YTHDF1 OS 6 1.21 0.67–2.18 0.532 72.10% 0.003 Random
YTHDF2 OS 3 0.9 0.52–1.57 0.715 80.10% 0.007 Random

Abbreviations: CI: confidence interval; HR: hazard ratio; OS: overall survival; DFS: disease-free survival.