Table 2. Summary of the meta-analysis of m6A regulators and prognosis in cancer patients.
Regulators | Outcome | Studies | HR | 95% Cl | P-value | Heterogeneity | Effects model | |
I2 | P-value | |||||||
METTL3 | OS | 21 | 1.75 | 1.32–2.31 | 0 | 78.10% | 0 | Random |
DFS | 7 | 2.02 | 1.54–2.64 | 0 | 52% | 0.052 | Random | |
METTL14 | OS | 4 | 0.55 | 0.43–0.69 | 0 | 0.00% | 0.392 | Random |
KIAA1429 | OS | 2 | 2.35 | 1.40–3.93 | 0.001 | 37.20% | 0.207 | Random |
METTL16 | OS | 2 | 1.75 | 0.84–3.65 | 0.137 | 82.20% | 0.018 | Random |
ALKBH5 | OS | 8 | 1.09 | 0.75–1.57 | 0.657 | 62.50% | 0.009 | Random |
FTO | OS | 10 | 1.01 | 0.72–1.41 | 0.966 | 74.70% | 0 | Random |
YTHDF1 | OS | 6 | 1.21 | 0.67–2.18 | 0.532 | 72.10% | 0.003 | Random |
YTHDF2 | OS | 3 | 0.9 | 0.52–1.57 | 0.715 | 80.10% | 0.007 | Random |
Abbreviations: CI: confidence interval; HR: hazard ratio; OS: overall survival; DFS: disease-free survival.