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. 2022 Nov 15;2(6):653–665. doi: 10.1016/j.jacasi.2022.08.015

Table 2.

A Summary of Several Studies on Lp(a) Cutoff Values in Chinese Populations

Population Sample Size Primary Endpoint High Lp(a) vs Low Lp(a) Main Conclusions Lp(a) Cutoff
Healthy population receiving routine physical checkup16 9,238 Myocardial infarction Lp(a) <16.7 mg/dL vs Lp(a) ≥16.7 mg/dL High Lp(a) is significantly correlated with myocardial infarction 17 mg/dL
Patients with a history of CAD37 7,562 Recurrent CVE The first tertile of Lp(a) levels (<8.88 mg/dL) vs the third tertile (≥26.45 mg/dL) High Lp(a) is independently correlated with the risk of recurrent CVE 26.45 mg/dL
Stable CAD patients with a history of PCI43 4,078 CVE Lp(a) <15 mg/dL vs Lp(a) ≥30 mg/dL High Lp(a) is correlated with CVE 30 mg/dL
Patients with a history of MI45 3,864 CVE The first quartile of Lp(a) levels (<8.19 mg/dL) vs the third quartile (18.84-41.43 mg/dL) The cumulative rates of CVEs and cardiac mortality were significantly higher in patients with high Lp(a) levels 18.84 mg/dL
Population aged >40 y and receiving routine physical check-up26 8,500 Stroke Lp(a) <26 mg/dL vs Lp(a) ≥26 mg/dL High Lp(a) is significantly correlated with stroke 26 mg/dL
Patients with ischemic stroke (ischemic and hemorrhagic)38 2,149 Stroke The first quartile of Lp(a) levels (<4.6 mg/dL) vs the fourth quartile (≥23.2 mg/dL) High Lp(a) is positively correlated with ischemic and hemorrhagic ischemic stroke 23.2 mg/L

CVE = cardiovascular event; MI = myocardial infarction; PCI = percutaneous coronary intervention; other abbreviations as in Table 1.