Figure 6.

tNMR under normoxia reduces extracellular acidification rate in synchronized NIH3T3 cells

(A) OCR of sham and tNMR treated cells, measurement starting immediately after treatment under normoxic conditions,

(B) Non-mitochondrial O₂ consumption, basal respiration, maximal respiration, proton leak, ATP production, spare respiratory capacity, spare respiratory capacity as a % of maximal respiration and coupling efficiency of normoxic cells.

(C and D) ECAR of sham and tNMR treated cells and (D): glycolysis, glycolytic capacity, glycolytic reserve and non-glycolytic acidification of normoxic cells, shown are means ± SEM, n = 3 to 5; asterisks mark significant differences between sham and tNMR treated cells under normoxia, calculated by two-way ANOVAs (GraphPad Prism 6.0).