Table 4.
Prognostic Impact Of Presence Of Tumor Thrombi as Well as Thrombotic and Bleeding Events
| VTE HR (95% CI) |
MB HR (95% CI) |
Mortality HR (95% CI) |
||||
|---|---|---|---|---|---|---|
| Unadjusteda | Adjusteda | Unadjusteda | Adjusteda | Unadjusteda | Adjusteda | |
| TT (yes vs no)b | 7.77 (4.03-14.95) | 6.61 (3.18-13.73) | 2.38 (1.21-4.70) | 1.69 (0.82-3.50) | 3.18 (2.18-4.64) | 1.65 (1.12-2.45) |
| ATE (yes vs no)b | N/Ac | N/Ac | 4.59 (0.63-33.58) | 3.49 (0.46-26.57) | 3.49 (1.11-11.00) | 6.29 (1.90-20.84) |
| VTE (yes vs no)b | N/A | N/A | 6.08 (2.56-14.45) | 4.67 (1.91-11.41) | 4.61 (2.77-7.67) | 2.87 (1.70-4.84) |
| MB (yes vs no)b | 1.93 (0.46-8.07) | 1.64 (0.39-6.94) | N/A | N/A | 2.49 (1.38-4.52) | 1.96 (1.08-3.57) |
ATE = arterial thromboembolism; other abbreviations as in Table 3.
a
Unadjusted HR derived from univariable Cox regression analysis. Adjusted HR derived from multivariable Cox regression, with adjustment for age, sex, Fuhrman grade, Karnofsky score and distant metastases at diagnosis.
b
Time-dependent variable.
c
Insufficient ATE events to perform statistical analysis.