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. 2022 Oct 18;4(4):491–503. doi: 10.1016/j.jaccao.2022.07.006

Table 2.

Peak Oxygen Uptake Postchemotherapy, Postintervention, and 1-Year Postintervention

Baseline
Postchemotherapy
Postintervention
1 Year Postintervention
Mean ± SD n Mean ± SD n Within-Group Difference vs Baseline (95% CI) Mean ± SD n Within-Group Difference vs Baseline (95% CI) Mean ± SD n Within- Group Difference vs Baseline (95% CI)
All
 Group A 30.4 ± 8.2 132a 28.3 ± 6.7 108 −2.8 (−3.5 to −2.0) 31.5 ± 7.9 106 +0.2 (−0.5 to 1.0) 32.0 ± 8.4 102 +0.5 (−0.4 to 1.3)
 Group B 29.7 ± 8.4 132b 24.1 ± 7.2 118 −5.8 (−6.6 to −5.1) 30.9 ± 9.2 99 +0.6 (−0.1 to 1.4) 30.5 ± 9.5 103 +0.2 (−0.7 to 1.0)
Testicular cancer
 Group A 36.3 ± 7.9 48 32.5 ± 6.8 40 −4.4 (−5.8 to −3.1) 36.8 ± 7.8 40 −0.2 (−1.6 to 1.2) 38.2 ± 7.9 40 +1.2 (−0.4 to 2.8)
 Group B 37.6 ± 7.6 47 28.8 ± 7.6 42 −9.1 (−10.4 to −7.8) 38.9 ± 8.4 35 +0.9 (−0.6 to 2.4) 39.0 ± 8.4 36 +0.5 (−1.2 to 2.1)
Breast cancer
 Group A 28.0 ± 6.2 69a 25.9 ± 5.6 59 −2.6 (−3.4 to −1.9) 28.6 ± 6.1 56 −0.1 (−1.0 to 0.7) 28.6 ± 5.8 54 −0.3 (−1.3 to 0.7)
 Group B 25.3 ± 5.1 68b 21.1 ± 5.4 63 −4.5 (−5.3 to −3.8) 26.5 ± 6.3 54 +0.2 (−0.7 to 1.0) 25.6 ± 6.4 56 −0.5 (−1.4 to 0.5)
Colon cancer
 Group A 22.3 ± 3.2 14 25.4 ± 2.5 9 +1.8 (0.1 to 3.6) 25.9 ± 5.5 10 +3.1 (0.7 to 5.5) 24.6 ± 5.5 8 +1.3 (−1.2 to 3.8)
 Group B 25.4 ± 5.4 16 23.6 ± 5.7 13 −1.6 (−3.1 to −0.1) 26.1 ± 5.6 10 +1.8 (−0.6 to 4.1) 27.4 ± 5.7 11 +2.4 (0.2 to 4.6)

The shown within-group differences are estimates extracted from the linear mixed-effects models. In group A, exercise intervention was initiated during chemotherapy; in group B, exercise intervention was initiated after chemotherapy.

a

1 baseline measurement of peak oxygen uptake had to be stopped early because the patient did not tolerate the mouthpiece. This patient was considered a dropout at time 0.

b

1 baseline measurement was not measured correctly because of technical difficulties.