Table 2.
Peak Oxygen Uptake Postchemotherapy, Postintervention, and 1-Year Postintervention
Baseline |
Postchemotherapy |
Postintervention |
1 Year Postintervention |
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---|---|---|---|---|---|---|---|---|---|---|---|
Mean ± SD | n | Mean ± SD | n | Within-Group Difference vs Baseline (95% CI) | Mean ± SD | n | Within-Group Difference vs Baseline (95% CI) | Mean ± SD | n | Within- Group Difference vs Baseline (95% CI) | |
All | |||||||||||
Group A | 30.4 ± 8.2 | 132a | 28.3 ± 6.7 | 108 | −2.8 (−3.5 to −2.0) | 31.5 ± 7.9 | 106 | +0.2 (−0.5 to 1.0) | 32.0 ± 8.4 | 102 | +0.5 (−0.4 to 1.3) |
Group B | 29.7 ± 8.4 | 132b | 24.1 ± 7.2 | 118 | −5.8 (−6.6 to −5.1) | 30.9 ± 9.2 | 99 | +0.6 (−0.1 to 1.4) | 30.5 ± 9.5 | 103 | +0.2 (−0.7 to 1.0) |
Testicular cancer | |||||||||||
Group A | 36.3 ± 7.9 | 48 | 32.5 ± 6.8 | 40 | −4.4 (−5.8 to −3.1) | 36.8 ± 7.8 | 40 | −0.2 (−1.6 to 1.2) | 38.2 ± 7.9 | 40 | +1.2 (−0.4 to 2.8) |
Group B | 37.6 ± 7.6 | 47 | 28.8 ± 7.6 | 42 | −9.1 (−10.4 to −7.8) | 38.9 ± 8.4 | 35 | +0.9 (−0.6 to 2.4) | 39.0 ± 8.4 | 36 | +0.5 (−1.2 to 2.1) |
Breast cancer | |||||||||||
Group A | 28.0 ± 6.2 | 69a | 25.9 ± 5.6 | 59 | −2.6 (−3.4 to −1.9) | 28.6 ± 6.1 | 56 | −0.1 (−1.0 to 0.7) | 28.6 ± 5.8 | 54 | −0.3 (−1.3 to 0.7) |
Group B | 25.3 ± 5.1 | 68b | 21.1 ± 5.4 | 63 | −4.5 (−5.3 to −3.8) | 26.5 ± 6.3 | 54 | +0.2 (−0.7 to 1.0) | 25.6 ± 6.4 | 56 | −0.5 (−1.4 to 0.5) |
Colon cancer | |||||||||||
Group A | 22.3 ± 3.2 | 14 | 25.4 ± 2.5 | 9 | +1.8 (0.1 to 3.6) | 25.9 ± 5.5 | 10 | +3.1 (0.7 to 5.5) | 24.6 ± 5.5 | 8 | +1.3 (−1.2 to 3.8) |
Group B | 25.4 ± 5.4 | 16 | 23.6 ± 5.7 | 13 | −1.6 (−3.1 to −0.1) | 26.1 ± 5.6 | 10 | +1.8 (−0.6 to 4.1) | 27.4 ± 5.7 | 11 | +2.4 (0.2 to 4.6) |
The shown within-group differences are estimates extracted from the linear mixed-effects models. In group A, exercise intervention was initiated during chemotherapy; in group B, exercise intervention was initiated after chemotherapy.
1 baseline measurement of peak oxygen uptake had to be stopped early because the patient did not tolerate the mouthpiece. This patient was considered a dropout at time 0.
1 baseline measurement was not measured correctly because of technical difficulties.