Table 1.
Characteristics of clinical trials included in the study.
| Characteristics | Number (percentage) |
|---|---|
| Total number of trials | 45 |
| Total number of patients in the placebo arm | 5684 |
| Total number of patients evaluable for ORR in placebo arm | 4760 |
| Cancer types | |
| Lung | 5 (11%) |
| Colorectal | 7 (16%) |
| Prostate | 3 (7%) |
| Hepatocellular | 9 (20%) |
| Gastro-esophageal | 5 (11%) |
| Sarcoma | 4 (9%) |
| Others | 12 (27%) |
| Treatment type | |
| Immunotherapy | 4 (9%) |
| Targeted therapy | 36 (80%) |
| Hormone therapy | 4 (9%) |
| Chemotherapy | 1 (2%) |
| Previous treatment | |
| None (treatment naïve or first-line) | 6 (12%) |
| Yes (second and subsequent lines) | 39 (87%) |