Table 2.
Neoplasm characteristics and treatment details.
| Variablesa | No anastomotic leak (n = 137) | Anastomotic leak (n = 35) | p-Valueb |
|---|---|---|---|
| Tumor subtype | |||
| Squamous carcinoma | 10 (7.3) | 4 (11.4) | 0.4486 |
| Adenocarcinoma | 125 (91.2) | 30 (85.7) | |
| Other | 2 (1.5) | 1 (2.9) | |
| Tumor location | |||
| Cardia | 84 (61.3) | 23 (65.7) | 0.5403 |
| Lower 1/3 | 51 (37.2) | 11 (31.4) | |
| Middle 1/3 | 2 (1.5) | 1 (2.9) | |
| Clinical staging (T) | |||
| Tis | 1 (0.7) | 0 (0) | 0.0944 |
| T1 | 14 (10.2) | 4 (11.4) | |
| T2 | 17 (12.4) | 10 (28.6) | |
| T3 | 105 (76.6) | 21 (60.0) | |
| Pathologic staging (T) | |||
| T0 | 37 (27.0) | 7 (20.0) | 0.138 |
| Tis | 1 (0.7) | 1 (2.9) | |
| T1a | 7 (5.1) | 6 (17.1) | |
| T1b | 17 (12.4) | 6 (17.1) | |
| T2 | 20 (14.6) | 4 (11.4) | |
| T3 | 55 (40.1) | 11 (31.4) | |
| Clinical staging (N) | |||
| N0 | 60 (43.8) | 15 (42.9) | 1 |
| N1 | 77 (56.2) | 20 (57.1) | |
| Pathologic staging (N) | |||
| N0 | 92 (67.2) | 24 (68.6) | 0.6483 |
| N1 | 29 (21.2) | 5 (14.3) | |
| N2 | 12 (8.8) | 5 (14.3) | |
| N3 | 4 (2.9) | 1 (2.9) | |
| Clinical staging (M) | |||
| M0 | 135 (98.5) | 34 (97.1) | 0.4969 |
| M1 | 2 (1.5) | 1 (2.9) | |
| Pathologic staging (M) | |||
| M0 | 135 (98.5) | 33 (94.3) | 0.1844 |
| M1 | 2 (1.5) | 2 (5.7) | |
| Histologic grading | |||
| GX | 33 (24.1) | 5 (14.3) | 0.4972 |
| G1 | 25 (18.2) | 8 (22.9) | |
| G2 | 46 (33.6) | 15 (42.9) | |
| G3 | 33 (24.1) | 7 (20.0) | |
| Neoadjuvant chemoradiation | |||
| No neoadjuvant treatment | 18 (13.1) | 8 (22.9) | <0.0001 |
| Chemotherapy only | 50 (36.5) | 0 (0) | |
| Chemoradiation | 69 (50.4) | 27 (77.1) | |
| J-tube placed pre/intraoperatively | |||
| No | 37 (27.0) | 10 (28.6) | 0.8346 |
| Yes | 100 (73.0) | 25 (71.4) | |
| Luminal obstruction by neoplasm | |||
| No | 69 (50.4) | 26 (74.3) | 0.0131 |
| Yes | 68 (49.6) | 9 (25.7) | |
| Surgical anastomotic rings complete | |||
| No | 1 (0.7) | 3 (8.6) | 0.027 |
| Yes | 136 (99.3) | 32 (91.4) | |
| Intraoperative RBC transfusion | |||
| No | 136 (99.3) | 35 (100.0) | 1 |
| Yes | 1 (0.7) | 0 (0.0) | |
| Postoperative RBC transfusion | |||
| No | 129 (94.2) | 26 (74.3) | 0.0017 |
| Yes | 8 (5.8) | 9 (25.7) | |
| Operative time, min | 278 ± 101 | 283 ± 109 | 0.7646 |
J-tube = jejunostomy tube; RBC = red blood cell.
a
The sample mean ± SD is given for continuous variables, and number (percent) is given for categorical variables.
b
p-Values were obtained using Fisher's exact test or pooled t test.