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. 2022 Nov 22;17:5581–5600. doi: 10.2147/IJN.S376358

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© 2022 Mohan et al.

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Ex vivo anti-cancer efficacy of Pep-NPs on MCF7 tumor spheroids. (A) Graphical representation of average diameter of MCF7 tumor spheroids on time points, 0, 24 and 48 hours post treatment with B-PPN, Pep5, Pep5-PPN, and Pep5-TPPN (Data are represented as mean ±SD for n = 3 (****p < 0.0001). (B) Representative images of live dead assay on MCF7 tumor spheroids after 48 hours treatment with Pep5, Pep5-PPN, and Pep5-TPPN. Live cells were stained green with calcein and nuclei of dead cells with ethidium homodimer.