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. 2022 Feb 8;92(5):1381–1390. doi: 10.1038/s41390-022-01977-1

Table 1.

Participant and device characteristics at insertion (n = 200).

Variable PICC TIVD Non-tunnel Non-tunnel HD Tunnel non-cuff Tunnel HD Tunnel cuff Total

CVAD

Catheter days

119 (60)

2680

21 (10)

1659

18 (9)

151

5 (3)

40

7 (4)

276

5 (3)

292

25 (13)

1895

200

6993

Patient characteristics
Age
 Median [years] (IQR) 5 (2–10) 3 (3–10) 0.5 (0.1–5) 0.9 (0.5–5) 0.3 (0.2–3) 3 (3–16) 4 (1–8) 4 (0.1–10)
 Neonates (0–30 days) 0 0 1 (6) 0 0 0 1 (4) 2 (1)
 Infants (31 to <1 year) 15 (13) 1 (5) 10 (56) 3 (60) 5 (71) 0 5 (20) 39 (20)
 Children (1 to <12 years) 80 (67) 18 (86) 7 (39) 1 (20) 2 (29) 3 (60) 15 (60) 126 (63)
 Adolescent (12–18 years) 24 (20) 2 (10) 0 1 (20) 0 2 (40) 4 (16) 33 (17)
Primary diagnosisa
 Respiratory (non-CF) 52 (44) 3 (14) 0 0 1 (14) 0 0 56 (28)
 Oncology and hematology 17 (14) 17 (81) 1 (6) 3 (60) 0 1 (20) 16 (64) 55 (28)
 Cystic fibrosis 30 (25) 3 (14) 0 0 0 0 0 33 (17)
 General surgical 12 (10) 6 (29) 4 (22) 0 0 1 (20) 5 (20) 28 (14)
 Gastroenterology 8 (7) 0 4 (22) 2 (40) 2 (29) 3 (60) 6 (24) 25 (13)
 Coronary care/cardiac 8 (7) 0 4 (22) 0 1 (14) 1 (20) 1 (4) 15 (8)
 Hepatic 3 (3) 0 5 (28) 2 (40) 2 (29) 0 1 (4) 13 (7)
 Other 16 (13) 1 (5) 4 (22) 0 0 5 (100) 5 (20) 31 (16)
Previous CVADs (no.)
 1 14 (27) 8 (53) 3 (33) 0 0 0 9 (60) 34 (32)
 2–3 15 (29) 4 (27) 4 (44) 2 (50) 1 (20) 1 (20) 2 (14) 29 (27)
 4–5 7 (14) 2 (13) 1 (11) 0 1 (20) 1 (20) 2 (14) 14 (14)
 >5 16 (31) 1 (7) 1 (11) 2 (50) 3 (60) 3 (60) 2 (13) 28 (27)
Known occluded vesselsa
 Basilic 15 (87) 2 (10) 2 (11) 0 3 (43) 0 3 (12) 25 (13)
 Brachial 4 (4) 1 (5) 0 0 1 (14) 0 1 (4) 7 (4)
 Cephalic 2 (2) 1 (5) 0 0 0 0 1 (4) 4 (2)
 Axillary 2 (2) 1 (5) 1 (6) 0 2 (29) 0 2 (8) 8 (4)
 Internal jugular 1 (1) 0 1 (6) 2 (40) 1 (14) 1 (20) 1 (4) 7 (4)
 Other (e.g., subclavian) 4 (4) 0 2 (12) 2 (40) 1 (14) 1 (20) 1 (4) 11 (7)
Device characteristics
Vessel
 Basilic 85 (71)b 0 0 0 0 0b 0 85 (43)
 Brachial 18 (15) 0 0 0 0 0 0 18 (9)
 Cephalic 5 (4) 0 0 0 0 0 0 5 (3)
 Axillary 8 (7) 0 0 0 0 0 0 8 (4)
 Internal jugular 16 (76) 11 (61) 2 (40) 7 (100) 4 (80) 20 (80) 60 (30)
 Subclavian 5 (24) 2 (11) 0 0 0 5 (20) 12 (6)
 Femoral 2 (2) 5 (28) 3 (60) 0 0 0 10 (5)
Lumen numbers
 One 103 (87) 21 (100) 1 (6) 0 (0) 2 (29) 0 (0) 4 (16) 131 (66)
 Two 16 (13) 0 (0) 2 (11) 5 (100) 5 (71) 5 (100) 20 (80) 53 (27)
 Three 0 (0) 0 (0) 15 (83) 0 (0) 0 (0) 0 (0) 1 (4) 16 (8)
Clinician characteristics
Multiple insertion attempts
 2 14 (12) 1 (5) 0c 0 0 0 4 (16)b 19 (10)
 ≥3 5 (4) 0 0 0 1 (14) 0 1 (4) 7 (4)
Guidance
 Ultrasound 118 (99) 11 (52) 15 (83)b 4 (80) 7 (100) 2 (40) 11 (44) 166 (83)
 X-ray for confirmation 114 (96) 21 (100) 8 (44) 2 (40) 7 (100) 5 (100) 22 (88) 179 (90)
 X-ray during placement 5 (4) 4 (19) 0 0 0 1 (20) 8 (32) 18 (9)
 Cut down 0 0 1 (6) 0 0 0 4 (16) 6 (3)
Tip position
 Cavo-atrial junction 104 (87) 5 (24)d 1 (6)c 1 (20)c 5 (71) 2 (40) 7 (28)b 125 (63)
 Superior vena cava 12 (10) 8 (38) 5 (29) 0 2 (29) 1 (20) 13 (52) 41 (21)
 Right atrium 0 6 (29) 5 (29) 1 (20) 0 2 (40) 4 (16) 18 (9)
 Non-central 1 (1) 0 1 (6) 0 0 0 0 2 (1)
 Inferior vena cava 2 (2) 0 2 (12) 0 0 0 0 4 (2)
Procedural time
 Median [min] (IQR) 62 (46–82) 77 (58–89) 162 (78–298) 40 (40–57) 92 (74–119) 129 (71–149) 80 (66–137) 70 (53–98)
Dwell
 Median [day] (IQR) 14 (11–23) >90 (>90) 7 (1–13) 3 (1–13) 26 (9–77) 90 (8–>90) 90 (71–>90) 16 (11–63)
 In situ at study end (3 months) 6 (5) 17 (81) 0 0 1 (14) 3 (60) 18 (72) 45 (23)

CVAD central venous access device, HD hemodialysis, IQR Interquartile range, PICC peripherally inserted central catheter, TIVD totally implanted venous device.

aMultiple response options.

Missing data: b1 c3 d2.