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. 2022 Nov 24;9:18. doi: 10.1186/s40348-022-00151-1

Table 2.

Birth characteristics in newborns with SCFN

subgroups
All patients (n = 320) Normocalcaemia (n = 52) Hypercalcaemia (n = 146) Hypocalcaemia (n = 9) No information about calcium level (n = 113)
Sex N 307 50 138 8 111
    Male N (%) 149 (48.5) 24 (48) 65 (47.1) 1 (12.5) 59 (53.1)
    Female N (%) 158 (51.5) 26 (52) 73 (52.9) 7 (87.5) 52 (46.9)
Birth weight N 218 35 91 4 88
Mean ± SD 3606±759 3232±937 3873±650 2975±763 3638±560
APGAR score ≤ 3 N 115 19 68 3 15
    1 min N (%) 78 (61.4) 12 (46.2) 47 (68.1) 3 (66) 9 (59.3)
Complications that occurred during or in the first days after birth N 522 78 284 17 146
    Asphyxia N (%) 62 (11.9) 8 (10.3) 30 (10.6) 4 (23.5) 20 (13.7)
    Respiratory distress N (%) 49 (9.4) 10 (12.8) 26 (9.2) 2 (11.8) 11 (7.5)
    Meconium aspiration N (%) 48 (9.2) 3 (3.8) 35 (12.3) 0 (0.0) 10 (6.8)
    Meconium in amniotic fluid N (%) 41 (7.9) 6 (7.7) 18 (6.3) 3 (17.6) 14 (9.6)
    Hypoglycaemia N (%) 41 (7.9) 4 (5.1) 22 (7.7) 1 (5.9) 15 (10.3)
    Hypoxic-ischemic encephalopathy N (%) 35 (6.7) 8 (10.3) 21 (7.4) 1 (5.9) 5 (3.4)
    Cerebral seizures N (%) 27 (5.2) 4 (5.1) 18 (6.3) 0 (0.0) 5 (3.4)
    Sepsis or infection N (%) 22 (4.2) 0 (0.0) 11 (3.9) 0 (0.0) 11 (7.5)
    Hypoxaemia N (%) 20 (3.8) 0 (0.0) 10 (3.5) 0 (0.0) 8 (5.5)
    Peripheral cyanosis N (%) 20 (3.8) 5 (6.4) 7 (2.5) 0 (0.0) 8 (5.5)
    Tachypnea N (%) 14 (2.7) 2 (2.6) 5 (1.8) 2 (11.8) 5 (3.4)
    Hypotension N (%) 14 (2.7) 2 (2.6) 9 (3.2) 1 (5.9) 2 (1.7)
    Anaemia/thrombocytopenia N (%) 14 (2.7) 2 (2.6) 5 (1.8) 0 (0.0) 8 (5.8)
    Acute renal failure N (%) 10 (2.0) 2 (2.6) 7 (2.5) 0 (0.0) 1 (0.7)
    Foetal disstress N (%) 10 (2.0) 3 (3.8) 7 (2.5) 0 (0.0) 0 (0.0)
    Bradycardia N (%) 10 (2.0) 1 (1.1) 6 (2.1) 0 (0.0) 3 (2.1)
    Dystocia N (%) 5 (1.0) 3 (3.8) 0 (0.0) 1 (5.9) 1 (0.7)
    Further N (%) 80 (15.3) 13 (16.7) 48 (16.9) 2 (11.8) 17 (11.6)
Treatment of birth complications
 Drugs N (%) 78 (30.5) 14 (26.4) 37 (30.3) 3 (37.5) 24 (32.9)
 Intubation and ventilation N (%) 75 (29.3) 15 (28.3) 34 (27.9) 2 (25.0) 24 (32.9)
 Therapeutic hypothermia treatment N (%) 51 (19.9) 11 (20.8) 27 (22.1) 1 (12.5) 12 (16.4)
 Reanimation N (%) 46 (18.0) 11 (20.8) 23 (18.9) 1 (12.5) 11 (15.1)
 Coma N (%) 3 (1.2) 0 (0.0) 1 (0.8) 0 (0.0) 2 (2.7)
 Phototherapy N (%) 2 (0.8) 2 (3.8) 0 (0.0) 0 (0.0) 0 (0.0)
 Reduction of the intracranial pressure N (%) 1 (0.4) 0 (0.0) 0 (0.0) 1 (12.5) 0 (0.0)