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. 2022 Apr 1;30(6):2505–2520. doi: 10.1007/s10787-022-00973-5

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Effect of DAPA alone or in combination with DORSO or EX-527 on OVX/D-Gal-induced changes in the expression of a SIRT1, b Beclin1, c LC3B, d p-mTOR proteins in the hippocampus, and e corresponding western blots as well as f TFAM hippocampal content. Data were expressed as mean ± SD (n = 3–6). *vs. SO, ^@vs. OVX/D-Gal, ^#vs. DAPA, ^βvs. DAPA + DORSO (one-way ANOVA followed by Tukey’s post hoc test, P < 0.05)