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. 2022 Nov 1;30(6):2153–2165. doi: 10.1007/s10787-022-01093-w

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© The Author(s) 2022

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Fig. 7 — Photomicrograph of rat colonic tissue from A DSS group showing degenerative mucosal changes (blue arrow), hypertrophy of muscularis mucosa (black arrow), and congestion of submucosal blood vessel (red arrow), B LPS group showing few mucosal inflammatory cells infiltration (black arrow) and slight submucosal oedema (blue arrow), C DSS/LPS group showing mucosal degenerative changes (black arrow) with; damaged crypt, shortening of the mucosa, depletion of mucous glands, and inflammatory cells infiltration (white arrow); degeneration of the muscularis externa (red arrow), and formation of crypt abscesses (blue arrows), D DSS/LPS group showing degenerative mucosal changes with massive lymphocytes infiltration (black arrows) which extended to the submucosa (red arrow), (H & E 100×)