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. 2022 Jul 13;30(6):2181–2195. doi: 10.1007/s10787-022-01025-8

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Effect of treatment with prednisolone or chromium on CFA induced changes in histopathology of hind paws. a Intra articular exudate, b synovitis, c cartilage erosions (three parameters are scored 0–3), and d number of FOXP3 positive cells by immunohistochemistry/HPF. **: Significantly different in comparison to control rats (P ≤ 0.001), ^##significantly different in comparison to untreated RA rats (P ≤ 0.001), ^@significant difference between both treated groups (P ≤ 0.05)