Table 2.
Incidence of adverse events after vaccination in healthy group and comorbidities group.
| Healthy (N = 229) | Comorbidities (N = 740) | Total (N = 969) | P valuea | |||||
|---|---|---|---|---|---|---|---|---|
| 40~59 years old (N = 121) | ≥60 years old (N = 108) | 40~59 years old (N = 297) | ≥60 years old (N = 443) | 40~59 years old (N = 418) | ≥60 years old (N = 551) | 40~59 years old | ≥60 years old | |
| Total adverse events | 20 (0.17) | 12 (0.11) | 81 (0.27) | 69 (0.16) | 101 (0.24) | 81 (0.15) | 0.0231 | 0.2895 |
| Local reactions | 17 (0.14) | 5 (0.05) | 61 (0.21) | 41 (0.09) | 78 (0.19) | 46 (0.08) | 0.1302 | 0.1722 |
| Pain | 15 (0.12) | 5 (0.05) | 59 (0.20) | 35 (0.08) | 74 (0.18) | 40 (0.07) | 0.0893 | 0.3035 |
| Induration | 0 (0.00) | 0 (0.00) | 5 (0.02) | 3 (0.01) | 5 (0.01) | 3 (0.01) | 0.3275 | 1.0000 |
| Swelling | 3 (0.02) | 0 (0.00) | 5 (0.02) | 5 (0.01) | 8 (0.02) | 5 (0.01) | 0.6956 | 0.5886 |
| Redness | 0 (0.00) | 0 (0.00) | 2 (0.01) | 1 (0.00) | 2 (0.00) | 1 (0.00) | 1.0000 | 1.0000 |
| Rash | 0 (0.00) | 0 (0.00) | 2 (0.01) | 1 (0.00) | 2 (0.00) | 1 (0.00) | 1.0000 | 1.0000 |
| Itching | 0 (0.00) | 0 (0.00) | 3 (0.01) | 6 (0.01) | 3 (0.01) | 6 (0.01) | 0.5599 | 0.6031 |
| Systemic reactions | 6 (0.05) | 7 (0.06) | 40 (0.13) | 33 (0.07) | 46 (0.11) | 40 (0.07) | 0.0099 | 0.8383 |
| Acute allergy | 0 (0.00) | 0 (0.00) | 3 (0.01) | 4 (0.01) | 3 (0.01) | 4 (0.01) | 0.5599 | 1.0000 |
| Skin & mucosa abnormalities | 0 (0.00) | 0 (0.00) | 1 (0.00) | 4 (0.01) | 1 (0.00) | 4 (0.01) | 1.0000 | 1.0000 |
| Diarrhoea | 1 (0.01) | 0 (0.00) | 2 (0.01) | 1 (0.00) | 3 (0.01) | 1 (0.00) | 1.0000 | 1.0000 |
| Anorexia | 0 (0.00) | 1 (0.01) | 4 (0.01) | 1 (0.00) | 4 (0.01) | 2 (0.00) | 0.3284 | 0.3539 |
| Vomiting | 0 (0.00) | 0 (0.00) | 2 (0.01) | 1 (0.00) | 2 (0.00) | 1 (0.00) | 1.0000 | 1.0000 |
| Nausea | 0 (0.00) | 0 (0.00) | 5 (0.02) | 1 (0.00) | 5 (0.01) | 1 (0.00) | 0.3275 | 1.0000 |
| Muscle pain | 1 (0.01) | 0 (0.00) | 12 (0.04) | 6 (0.01) | 13 (0.03) | 6 (0.01) | 0.1203 | 0.6031 |
| Headache | 0 (0.00) | 1 (0.01) | 7 (0.02) | 5 (0.01) | 7 (0.02) | 6 (0.01) | 0.2005 | 1.0000 |
| Cough | 1 (0.01) | 0 (0.00) | 4 (0.01) | 2 (0.00) | 5 (0.01) | 2 (0.00) | 1.0000 | 1.0000 |
| Fatigue | 3 (0.02) | 6 (0.06) | 26 (0.09) | 22 (0.05) | 29 (0.07) | 28 (0.05) | 0.0199 | 0.8075 |
| Fever | 0 (0.00) | 0 (0.00) | 2 (0.01) | 2 (0.00) | 2 (0.00) | 2 (0.00) | 1.0000 | 1.0000 |
aThe p-value was calculated by Fisher’s exact probability method.