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. 2022 Nov 24;15:441. doi: 10.1186/s13071-022-05565-4

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Analysis of the KEGG pathway. a–dThe top 20 pathways enriched by genes regulated by differentially expressed lncRNAs, mRNAs, miRNAs in HCT-8 cells at 3 hpi. e–i The top 20 pathways enriched by genes regulated by differentially expressed lncRNAs, mRNAs, miRNAs, circRNA in HCT-8 cells at 12 hpi. The vertical axis represents the pathway name and the horizontal axis represents the gene ratio. The size of the filled circle represents the number of differentially expressed genes in the pathway, and the color of the filled circle corresponds to the different -log₁₀ (P-value) ranges. KEGG, Kyoto Encyclopedia of Genes and Genomes