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Xenograft tumorigenesis assay in nude mice. A Subcutaneous xenograft volumes and B weights were measured in mice injected with A549 cells stably expressing sh-NC and shRNA targeting circ_0017109. C Protein levels of cleaved caspase-3, FZD4, β-catenin, non-phospho β-catenin, Bcl-2, c-myc and cyclin D1 in xenograft tumor tissues with sh-NC or shRNA targeting circ_0017109. ***, P < 0.001
